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Analysis of H2AX-positive cells after cisplatin treatment showed that A549 cells had a low induction of DNA damage, while the NCI H23 lineage had a high induction at 6 h of treatment and displayed a threefold increase after 24 h
Plasma enzyme assay and liver histology Plasma was extracted from whole blood and immediately measured for alanine aminotransferase (ALT) and aspartate aminotransferase (AST) activities using a biochemical kit (Diagnostic Chemicals Ltd., Oxford, CT)
A review published in Cureus (2024) noted that while TB-500 shows promise for soft tissue regeneration, additional research is necessary before clinical translation can occur
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